Feline Hyperthyroid Treatment

Evaluations, treatment and care.

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Treatment Options

The three accepted treatment options are described below:

Tapazole (Methimazole, Felimazole)

An anti-thyroid medication given orally which blocks thyroid hormone production. It does not cure the disease, so in order to be effective, this medication must be given for the life of the cat. Possible side effects of tapazole therapy include vomiting, lethargy, loss of appetite and various blood diseases. The most common reasons for failure of long-term treatment with tapazole are the lack of owner compliance in giving the medication and the cat’s unwillingness to take It.

Thyroid Gland Surgery

This option Is not without potential problems in hyperthyroid cats. Anesthesia carries higher risk in patients over the age of 12 years which Is the typical age of most hyperthyroid cats. Removal of one thyroid gland can cure the symptoms; however, often tumors develop in the other gland necessitating a second surgery. Cats who have had surgery on both glands often require supplementation (medication given twice daily) for life.

Radioactive Iodine (I-131)

No anesthesia is required for this treatment and a single injection Is curative in 95-98% of the cats treated. There are no side effects associated with radioactive iodine therapy. This treatment does require a hospital stay of about five days.

Pre-Treatment Evaluation

Laboratory work, x-rays and physical exams can be done by the referring veterinarian. This information must be current. within thirty days of treatment. Diagnostic tests required include:

  • Complete physical exam
  • Complete blood count with differential
  • Serum biochemistry profile
  • Urinalysis
  • T4 level at the time of diagnosis

It may also be recommended that chest x-rays, electrocardiogram, and echocardiography be preformed in addition to the above laboratory work, if there is any indication of an existing heart condition (murmur, arrhythmia, etc.). The cost of the pre-treatment evaluation, if performed at the treatment center, is not included in the treatment cost.

Pre-Treatment Evaluation

Laboratory work, x-rays and physical exams can be done by the referring veterinarian. This information must be current. within thirty days of treatment. Diagnostic tests required include:

  • Complete physical exam
  • Complete blood count with differential
  • Serum biochemistry profile
  • Urinalysis
  • T4 level at the time of diagnosis


It may also be recommended that chest x-rays, electrocardiogram, and echocardiography be preformed in addition to the above laboratory work, if there is any indication of an existing heart condition (murmur, arrhythmia, etc.). The cost of the pre-treatment evaluation, if performed at the treatment center, is not included in the treatment cost.

Post Treatment Care

Once your cat Is released to you, it must be confined to your house for two weeks. For these two weeks it Is required that pregnant women or anyone under 18 years of age must not come in contact with your cat. If necessary, your cat can be boarded at our hospital for the two weeks at an additional cost. According to DHEC regulations, your cat may not be boarded at any other facility for these two weeks.

Cat litter must be disposed of daily using gloves and a litter pan liner. We recommend that handling your cat Is kept to a minimum; In keeping within these guidelines, we recommend washing your hands after petting your cat and not allowing him/her to sleep in your bed for the two week period. It Is fine for your cat to be around your other pets. They can share food, water and litter boxes. Thyroid levels must be checked at one and three months post treatment. This bloodwork can be done by the veterinarian who has referred your cat to the treatment center.

Post Treatment Care

Once your cat Is released to you, it must be confined to your house for two weeks. For these two weeks it Is required that pregnant women or anyone under 18 years of age must not come in contact with your cat. If necessary, your cat can be boarded at our hospital for the two weeks at an additional cost. According to DHEC regulations, your cat may not be boarded at any other facility for these two weeks.

Cat litter must be disposed of daily using gloves and a litter pan liner. We recommend that handling your cat Is kept to a minimum; In keeping within these guidelines, we recommend washing your hands after petting your cat and not allowing him/her to sleep in your bed for the two week period. It Is fine for your cat to be around your other pets. They can share food, water and litter boxes. Thyroid levels must be checked at one and three months post treatment. This bloodwork can be done by the veterinarian who has referred your cat to the treatment center.